tried simple and ezportal, wasn't satisfied with both
looking at tinyportal it seems much more cms-like, but support in their site looks very confusing and cryptic
anyway most if not all portal software look the same no matter what you prefer.
simpleportal - looks great and simple, easy to use great support and lots of people sharing codes and what not
ezportal - great if you have vbgamers mods and want no problems with them, also if you dont mind really blocky looking blocks with no chance of any extra bells and whistles
tinyportal seems to work in the middle of both, it has support for alot of vbgamers and other dev mods (but not all), highly customizable(if you can code and style) and looks pretty in a no-nonsense, professional way.
I like simpleportal but it looks too much like it's for kids and gamers, tiny if you want to be taken more seriously

, ezportal well, if you want your mods to run since he made both.